Exactly what WWB said.
I have both or all three on my rental counter at the range and all are good guns and very reliable and for the most part will never wear out.
But as he said, the MK11 is the hands down favorite for nearly every use you may have. You may want to consider the 22/45 in the MK11 for a little different grip and mag release function. But as he said, the MK11 will give you trouble free, accurate, long life and they are not as finicky about the ammo you put through them as are most all other 22 pistols.
I use one or the other of the CCI rounds for our rentals as they feed through almost every 22 handgun or rifle that we see in our range.
Many of the 22 pistols will burp or stop altogether until you find the right ammo for them. I have given up on all of the Remington and Winchester, 22 ammo and I have even quit selling them as too many people were experiencing too many troubles with either or both. So, for what it is worth, stay with one of the rounds offered by CCI, (stinger, Velocitor) etc. to get the best of the day to day ammo for your gun. If you get into serious, competition target shooting, you will probably change to an entirely different and more expensive firearm.
The other thing is to remember what to do to make them even more accurate than there are from the factory. Once you have the gun of your choice and if you then find that you want to accessorize or accurize or both, go to the Volquartzen catalog and load it up.
Hope this gives you more ideas or answers to help with your decisions.
UF